Friday, June 29, 2007
UNIT II- Self and Unit Evaluation
Thursday, June 28, 2007
UNIT II- Exercise Physiology LAB
Exercise, Exercise, Exercise- unit II-Lab
This Lab project was based on measuring metabolic rates of pulse, respiration, and systolic/diastolic BP. Not only do our bodies work hard at rest, but when you add a cardiovascular workout on top of it; double time steps in! Beginning this lab, I measured my rates at rest 5 different times, calculated each mean, and then performed 3 activities/3 reps each: step aerobics, vacuuming, and swimming. During exercise, the cardiovascular system works hard to increase the blood flow due to the high demand of energy. Having some knowledge about the cardiovascular system, it only makes sense to conclude that during each activity; the pulse, respiration and BPs would have a slight increase in their measurements (depending on the exertion of the exercise). One of the important cells in the cardiovascular system is the RBC, in that it carries oxygen, which diffuse into tissues. I will quickly review what the numbers of systolic and diastolic pressure are. While using the blood pressure cuff to measure my blood pressure; the first notable beat, after pumping it up, is the systolic measurement (contraction of the heart) and the last beat is the diastolic measurement(relaxation of the heart). I hope by reading through this lab, you will have an understanding of what happens to your metabolic measurements during exercise and what causes the changes.
Before starting this lab, I wrote down an 'educated guess' for each activity, what I thought my metabolic measurements would be. Since I perform these activities, I felt comfortable formulating a hypothesis for each metabolic rate, stating that my pulse, respiration's, and BP would increase. Knowing that swimming is more physical exertion, I guessed my measurements would increase more than step aerobics and vacuuming. The table to the right are my formulated guesses. As mentioned above, our bodies supply oxygen and blood to the heart during the high energy demand while exercising. With my activities, my hypothesis and the outcomes were fairly accurate.Materials and Methods. An average resting heart rate is between 60-100 bpm. "The heart rate adapts to changes in the body's need for oxygen" (American heart article). An example of this would be during the exercises I performed. There are several places to get a pulse measurement a few places are :carotid, femoral, brachial, popliteal(behind the knee), and radial. I used my radial pulse, which is shown in the picture to the right (the sticker is where I placed my fingers). For each activity my heart rate increased, more after each rep, due to the heart pumping faster, in need of more oxygen. During these activities the throbbing sensation while exercising is the arteries responding to the heart beat, which is carrying blood away from the heart. The second measurement were my respiration's, which is counting each full breath in and out. (I did not take a picture, because you wouldn't be able to see it anyway). An average RR(respiratory rate) for an adult is 12-20, depending on the individual. During an inhalation, we breath in oxygen from the environment which contains "20% oxygen," which mixes with the oxygen in our alveloi containing "14% oxygen" (respiration, article). The main function of respiration is to quickly send oxygen to our blood and in return quickly removing carbon dioxide. This happens with an individual who has a healthy set of lungs. Working in the health care field, I have seen many individuals that can't perform this cycle without gasping for air. Some individuals have difficulties breathing while trying to talk, changing positions, or even eating. This most commonly occurs with Emphysema and individuals with congestive heart failure. Instead of having thin, small alevoli for exchange; these individuals are living with larger surface areas and alveloi. Making them short of breath with minimal exertion. During a deep inhale and exhale the body can take in and remove about "5.5 Liters of air" (respiration). Again with each rep on my activities, my respiration's increased. The more physical and strength I put in the more work my heart pumped to supply my blood flow. The third metabolic measurement was my blood pressure(systolic and diastolic). "Blood pressure is the force of blood pushing against the walls of the arteries" (wikipedia). An average BP reading for adults is 120/80 or lower. The picture below and to the right shows where I placed my blood pressure cuff and my stethoscope( As you can see I took it myself so it was a bit tricky). I felt for my brachial pulse, placed my stethoscope on that area and pumped to about 180. I also put a picture of my stethoscope and blood pressure cuff below.
Increased physical activity causes an increase in pressure in the body, this forces the heart to supply oxygen rich blood to the main chambers of the heart(aorta, ventricle). This blood then branches to arteries, then arterioles. The smallest branching is known as the capillaries(where the pressure of blood decreases) supplying the body with refreshing oxygen/nutrients. While swimming my laps the faster my strokes became, the more blood was pumping through, increasing my blood pressure. These measurements will be found in the table below. Once the oxygen is delivered to the tissues in the body, deoxygenated blood starts the journey pumping back to the heart(which is found in the capillaries). Similar to the branching of the arteries; the capillaries branch into veins, venules, and the superior/inferior vena cavas. Measurements of blood pressure can vary depending on each individual, activity, temperature, posture, diet, history, and medications. Again, this lab shows that with the activities I picked, my measurements increased.
This picture shows the step aerobic exercise I did (50/rep). For this activity, my metabolic guess was fairly accurate. For each metabolic measurement my rates increased. My pulse was the highest change. I started at 72bpm and at my last rep it was 104. Below you will see the graph mean for this activity.
This picture is to show my second activity, I was vacuuming. It was more than this little area. (which is now neatly cleaned after 3 times)!
This obviously shows my third activity, swimming. I did 6 laps for each rep(before all the kids came and ruined my peace fullness :) )
Data.
The table above shows the metabolic rates of each activity I performed 3 times and the right column is the mean measurements for: pulse, respiration, and systolic/diastolic BP. At the bottom(read area) is actually already mentioned above, its my hypothesis results. The bar graph to the right is the mean results for each activity. For each activity the mean measurements were accurate and what I expected.
Analysis of data. Activity One(step aerobics) hypothesis was correct. My guesses were: 84-20-125-70. The mean results were: 88-21-124-70. According to the data I collected, this is what I was expecting. My pulse ranged, but that could have been depending on the pace I did for each rep. Activity Two (vacuuming) hypothesis was not correct, it was a little off. My guesses were: 72-16-116-70. The mean results were: 88-21-118-70. Again, my pulse was more than what I though it would be. Also my hypothesis respiration's were lower than the mean average. I guess vacuuming is more work that I expected it to be. But the BP were fairly close. Activity Three (swimming) hypothesis were somewhat correct and close. My guesses were: 120-24-130-75. The mean results were: 120-23-127-73. Now that I am looking back, I would think that my BP would be more. I retook my 3rd systolic pressure twice, and got 120; which was surprising. By my third rep I could have slowed down, possibly making it lower. My hypotheses on all three activities were fairly correct when comparing them to my mean averages. Our bodies continue working with each activity we participate in, most likely increasing each metabolic measurement.
Problems with your data or technique. There are a couple things that could change the measurements. As I mentioned above, moving at the same exact pace for each activity wasn't the case, which could change the numbers slightly. Another point I would like to make is, which measurement to take first. By the time I got my pulse and respiration's done, and adjusted my BP cuff my measurements may have went down a little. Regardless I feel that my results are correct, and I did not have any technical difficulties to bother with. Above I reviewed my hypotheses and mean results, and even though some are a little off I still think that they are fairly accurate or correct.
In conclusion I would like to say this lab was interesting and fun. Doing all these activities and then thinking about why my metabolic rates changed is fascinating. It's something I don't typical stop to think about! Starting the lab, I already had the feeling that each metabolic measurement: pulse, respiration, and BP would slightly increase depending on my activities. The more exertion I gave, the higher my results were. But, if we were able to look inside of our bodies it would all make sense. Our baby alveloi branching off of our lungs are tiny, but they quickly take in oxygen and remove the unwanted carbon dioxide. This in turn, keeps our respiratory cycle functioning. When there is more physical activity, our heart pumps faster causing our arteries to fill up and send blood to the heart. Oxygen and nutrients are delivered while carbon dioxide and wastes are removed. The cardiovascular system can be complex, but knowing that our heart is aware of the increase in activity; it continues to pump faster to supply blood to carry oxygen and nutrients to cells and tissues. During these exercise, I could feel the beating sensation of my heart; knowing it pumps harder to supply oxygen to the muscles is amazing. Our heart truly is a loving structure.
Works Cited:
http://www.puchon.com/biology/respire.htm#ventricle
quote
http://en.wikipedia.org/wiki/blood_pressure
quote
www.americanheart.org/presenter.jhtml
quote
Tuesday, June 26, 2007
UNIT TWO: Ethical Essay
A SCRUMPTIOUS MEAL-Ethical Essay
What would taste better to you: A home cooked pot of simmering stew, or frozen stew from a bag heating above the stove? We all have different opinions and experiences, but in my opinion I would rather peel and cut the vegetables than tear open a bag and plop the stew in water. The food industry is becoming more popular with developing "homemade" meals into a meal quick and easy. Nutrition is an important part of our lives, and learning which foods are essential and where you can find them, would be beneficial to know. A few major points to discuss in this essay would be: where does our produce come from, the abundance of processed/packaged foods, and healthy versus "empty calorie" diets. Are individuals paying attention to what they are eating? Our bodies need the nourishment to stay healthy, but many food markets supply many unneeded produce that consumers continuously buy.
UNIT TWO: Nutrition Lab
To keep our bodies working to give us the strength and energy; it is important to feed our bodies. This lab was basically inputting what we ate throughout the course of a day, as the picture above shows. The end results are not accurate because it didn't ask for specific amounts, and I was unable to dictate the amount consumed and not everything was on the list. Some of the food I ate and entered are not the exact same product, but similar. At the end, it gives a table of the nutrient totals. Below I will discuss what I ate for the day and the total amounts for the nutrients
Breakfast: 1 slice of sourdough bread toasted with 2 TBLS of Peanut butter, 1 cup of coffee with a tsp of fat free vanilla creamer, 8 oz of water, and 8 0z of fat-free milk.
Snack: Nutri-grain bar(honey oat) 1 bottle of Gatorade
Lunch: Salad with fresh vegetables: 1/4cup of cucumbers and green peppers, tomatoes, sunflower seeds, and ranch dressing. Rye crisp with colby cheese. 16 oz of water
Snack: Green grapes- tostido chips/cheese dip. Water
Dinner: Chicken and cheese quesadila with 1 tsp of sour cream. 8 oz of water. Fresh fruit: honeydew, watermelon, and strawberries.
Snack: Chocolate Ice cream and strawberries
I drink a lot of water throughout the day!!!! And thankfully, lately I have had cravings for fresh fruit!!!!
The Table states that the total Calories: 1010, Fat:44g, Sat. fat:20, Cholesterol:110mg, Sodium:1970mg, Carbohydrate: 105g, Dietary Fiber 10g, Sugars: 36g, Protein: 52g. The Vitamin totals: Vitamin A: 160%, Vit. C: 80%, Calcium: 110%, and Iron 35% Like I mentioned before these totals could be more or less. I'm not sure that with what I gave, my total fats could equal 64! I didn't eat a whole chicken or pound of cheese in my quesadila!
1. How healthy of a diet do you think this is? I am pregnant so I have tried my best to improve my diet. For the most part I feel I have a healthy diet. Although the pictures on the lab show that I am a carbohydrate friendly, well-balanced, vegitarian. It also shows a picture of a vegan, but I do eat meats. We basically grill a lot of steaks, hamburgers and pork chops.
2. What would you change about this day's eating. If anything? I basically eat this on a routine basis. Some days more veggies or dairy products(yogurt, string cheese). Even though I think I drink a lot of water, I still could probably drink more. And focus on a healthy meat for dinner.
3. Do you find this kind of tracking helpful? Its helpful to a point, but I wouldn't keep checking my nutrition status with this set up. It doesn't give accurate amounts and not everything is listed. Looking at the values I didn't realize with the vitamins: amounts of fruits and veggies that I exceeded the percentage. (that's a good thing). But then again, it may not be accurate.
In conclusion, this lab helped reassure me the importance of maintaining a healthy "food pyramid" diet. Our bodies need the food to stay energized, maintain function, metabolism, and growth. Our bodies can not do this without our physical job of supplying the bodies daily requirements. The food I entered in the beginning is a usual diet I try and stick to; not only for me but for my baby. I don't feel it is necessary to 'eat for two' as long as I am able to eat a well-balanced meal. Nutrition is important, and I like to think I am eating well to support my points.
Monday, June 25, 2007
UNIT TWO: Compendium Review #2: Digestive System and Nutrition
Saturday, June 23, 2007
Unit II LAB- Blood Pressure
Tuesday, June 19, 2007
UNIT TWO: Compendium Review #1: Oxygen, Microbes, Immunity
It's typical to live each day, and not even realize the work load each system, cell, vessel, or organ performs to keep our bodies homeostatic and functioning. Above is a broad table of contents that I will do my best to describe and bring out the main points. The heart is a valuable part of our body, with each "lubdub" is a new flow of blood entering our systems. There is an abundant amount of cells flowing throughout our bodies, bringing oxygen and nutrients in and riding of wastes. Thankfully, we have WBCs that help fight off unwanted pathogens, they resemble an eagle when it hunts for food, it quickly swoops down and gathers its prey. We definitely need to appreciate the workload these cells do. The earth is full of organisms, microbes, that we need to be watchful for and appreciate the screening they do to our environment. Studying these chapters brings up the importance to keep our bodies healthy; doing our best to prevent the infectious diseases lingering around us each day.
CARDIOVASCULAR SYSTEM AND BLOOD VESSELS: The Cardiovascular system is like the ocean constantly full of swimmers. The swimmers (blood) move throughout the ocean(body) and the fish(other systems in the body) help keep the ocean functioning properly. A swimmer(blood) takes a break on the shoreline; brushes off seaweed (excess wastes), takes a sip of Gatorade(nutrients and oxygen) and dives back into the ocean. This scenario describes the process of the removal of carbon dioxide and the entrance of oxygen in the body. There are three types of blood vessels the book refers to. The picture to the right is of an artery(red) and vein(blue). 1) Arteries: a blood vessel that carries blood away from the heart toward a capillary. The walls are strong, which gives extra support when blood moves around. 2) Capillaries: a small, microscopic blood vessel with thin walls composed of an endothelium layer, gas and nutrient exchange takes place. 3) Veins: a blood vessel that carries blood from a capillary towards the heart. Veins have a valve(similar to a plug) which helps prevent back flow of blood. The walls are thin compared to arteries, meaning when blood enters at high pressures; it causes expansion.
The next main focus is the function of the heart: The heart is found between the lungs, behind the breastbone, about the size of your fist, and has 3 muscular layers surrounding it. The outer layer is the myocardium (cardiac muscle), pericardium(supports and protects), and the epicardium(outer layer). To describe the heart, look at the picture to the right. You will notice that there are four main chambers: Right atrium, right ventricle, left ventricle and left atrium. Also note the valves located between the chambers: their main function is to prevent blood back flow. Next I will discuss the passage of blood. Beginning the flow, blood enters the superior/inferior vena cava to the right atrium. The right atrium to the tricuspid valve-right ventricle-pulmonary valve-pulmonary trunk-divides into two pulmonary arteries(blood travels to the lungs/deoxygenated or poor blood). Oxygenated(rich blood) enters through the pulmonary veins-left atrium-bicuspid valve-left ventricle- aortic valve- aorta- different parts of body. The picture to the right is color coded, showing the entrance/exit of blood via the veins and arteries. "The human heart beats more than 3.5 billion times in an average lifetime" (wikipedia). These beats are more than "lub dub." Each of those beats is known as a cardiac cycle. During a beat, the atrias squeeze shut(systole) at the same time, and then the ventricles squeeze shut at the same time. Then it goes through a relaxation phase(diastole). When listening to a rhythmic heart through a stethoscope you will notice a "lub" sound, which is the increase pressure of blood, forcing the tricuspid valve to close. This in turn, causes the pulmonary and aortic valves to bounce open. The "dub" is the closing of these valves. "The SA node is called the pacemaker because it usually keeps the heartbeat regular" (Mader 90). A slow functioning SA node is usually fixed by placing an artificial pacemaker. ECG and EKGs can be used to view the heart rhythm for any possible signs of abnormalities. The pulse and blood pressure will be discussed in the lab portion.
Cardiovascular Pathway: The right side of the heart pumps blood to the pulmonary circuit( carbon dioxide is dumped off, and oxygen is the traveling partner). The left side of the heart pumps blood in to the systemic circuit(blood delivers oxygen and nutrients to tissues and discards wastes).
Capillaries: The layer of a capillary is an endothelial lining, meaning only small particles/molecules are capable of moving through. When blood enters the arteriole end(red section) water and molecules small enough to exit, move out of the lining due to an increase in blood pressure. By the time blood reaches the venule(blue section) water moves in by osmosis. In the middle of the capillary, there is no movement; therefore, oxygen and nutrients exit, carbon dioxide and wastes enter, and RBC/proteins remain inside. Cardiovascular disease continues to be the leading cause of death. HTN, atherosclerosis, stroke, and heart attack are a few examples.
CARDIOVASCULAR SYSTEM AND BLOOD: "The human body contains about 5 liters of blood, and the heart pumps this amount of blood with every beat!" (Mader 106). There are 3 main activities of blood: transportation(running oxygen and nutrients and supplying to other cells), defense(fighting foreign objects/preventing clots), and regulation(temperature and fluid/electrolyte). Blood travels everywhere throughout our bodies making sure we are ready to face our next big challenge. Whether the challenge is just getting out of bed in the morning, jogging around the block, replenishing our thirst, fighting a cold, or sleeping after a hard days work. During any of these examples, blood continues to flow to all of the systems within us. Their are two compostions of blood to discuss. The test tube picture to the right, shows the separation of the cell fragments. 1) formed elements: RBC(most abundant: delivers oxygen), WBC(work in the tissues: engulf/ defend against foreign objects), and platelets(stick together to form a plug: during a sudden blood loss). 2. Plasma: 90% of this water. Its main function is to transport nutrients and wastes throughout the system .
RBC: This is the most common blood cell that delivers oxygen to the lungs. Inside this cell are numerous copies of hemoglobin, which gives the cell its distinct, color and contains protein(globin) and iron(heme) chains. The Iron chain Each of these chains bind differently to oxygen. Notice in the picture to the right the RBC has an indented(bio concave) center, this helps move gases in and out of the cell "RBC's produce ATP anaerobically, and they do not consume any of the oxygen they transport" (Mader 108). Erythropoesis refers to the production of RBCs. The life span of a RBC is 120 days. An interesting amount of RBCs are destroyed each second, "2 million" (Mader 109). That shows how hard these little cells work to keep up with the demand of transporting oxygen and nutrients to different cells. A couple common RBC disorders are anemia, sickle-cell, hemolysis.
WBC: These cells were briefly touched on above, but are important in the immune system; fighting against infections. The two different types of WBC's are granular and agranular leukocytes. Granular are: Neutrophils( most abundant, quick at responding and remove the foreign particles), Eosinophils(help during allergic reactions), and Basophils(releases the chemical histamine). Agranular are: Lymphocytes(help defend the body, consist of 2 types: Natural killer cells(NK cells), Tcells, and B-cells which produce antibodies to help destroy the particles). Monocytes(important function is phagocytosis(eats away/ingests), and it responds quickly to the endangered site). WBC work at making sure the cell is not attacked by the unwanted particle.
MICROBES. Picture the rocks at the bottom of a fish tank, rocks beneath the soil, and rocks on the bed of a river. Flowing through these waters, are microscopic organisms known as microbes(bacteria, fungi). Not only are they found in water, but scattered everywhere on the earth. These microbes are both helpful and a threat to our lives. They help by acting as "decomposers" and are a threat since most microbes( bacteria) are the main source of the many diseases that kill humans. The picture to the right is bacteria, magnified many times over.
All of us have heard the phrase over and over that the number one thing to help stop the spread of infection is: HANDWASHING. Think about the last thing you touched. Was it shaking someones hand, touching your steering wheel, removing your shoe, or opening a door? Think of all the microscopic particles crawling around on that object!!! Bacteria multiply when the environment is suitable for them to grow.
Viruses are most commonly referred to when talking about the flu or cold. They infect cells and replicate when they infect a host cell. An interesting thing about viruses is that they carry genetic information, and protect it with a protein coat! To help stop the spread of a virus, is done be immunization. That is why it is important to be up-to-date on immunization. Scientists have studied this background for many centuries, viewing and trying to culture a viral organism. "In the late 19th century, Charles Chamberland, developed a porcelain filter with pores small enough to filter viruses, yet retain all viable bacteria" (Wikipedia). Research obviously has blossomed since then.
IMMUNITY. This defense mechanism helps ward off diseases from entering the body. It builds blockades, and send the WBCs to help engulf the unwanted particles. Antigens are referred to as: "molecules the immune system recognizes as foreign to the body" (Mader 130). The B cells and T cells are like sensors, they recognize antigens and bind to them with their receptors. Antibody-Mediated Immunity is the defense process of a B cell and its receptor making copies, which turn into plasma cells and memory B cells. Cell- Mediated Immunity is when T cells find help from others and then attack the diseased/cancerous cell(note the blue and red T cells below: found each other, and are now forming a plan to attack the green, infected blob to the right). Again, the cells work together to help cure, in this case, an infected cell. Cytotoxic T cells are like sticky glue, settling into a piece of foam: they bind to the infected cell, settle onto the membrane, puncture little pores, and suffocate the infectious cell. Helper T cells give out directions to cytokines(chemicals used for communication). A memory T cell stores information of a previous antigen occurring in the body, if it resembles the same antigen again, it will alarm other cells to activate. Fighting against these antigens can be a lot of work, but the cells manage to alarm those needed to help destroy the infectious antigen.
There are two types of acquired immunity to briefly touch on. Active immunity: Vaccines are used to help expose our bodies to a specific antigen. (Earlier I discussed the purpose of memory T cells, this is where they function) Children are recommended to receive immunizations to help prevent diseases (chicken pox, tetanus). Passive Immunity: This is a temporary immunity passed on from individual to individual.
AIDS/HIV. This disease, acquired immunodeficiency syndrome, was first discovered in 1981. Killing more than 25 million since its recognition in 1981(wikipedia). AIDS damages and weakens the immune system, caused by the human immunodeficiency virus (HIV). It is believed that HIV "originated from chimpanzees," in sub-Saharan Africa. The transmission is also thought to come from the blood of the chimpanzee transferring into the wound of a human (Biology). There is not a cure for this deadly disease, but some drugs are used for treatment and learning to be safe and use precaution measures help stop the spread of AIDS/HIV. Transmission of HIV is by direct contact of mucous, blood, and bodily fluids (semen,blood, vaginal fluid, and breast milk), contaminated needles, sexual intercourse, and blood transfusions. HIV destroys the T cells which are manditory to help keep the immune system functioning properly. When there is less than 200 microliters of these cells, it destroys the cell mediated immunity that helps recognize antigens(as mentioned earlier); leading to the well known condition: AIDS. A few symptoms related to AIDS are: fevers, night sweats, swollen glands, weakness, weight loss, and chills (wikipedia). Antiretroviral therapy is being used to help lengthen the life span of an individual infected with AIDS. Education continues to be an important concept to pass on to help stop the spread of this struggling disease.
In conclusion, I will tie what I stated in the beginning; studying these chapters definately makes me think more of what is happening inside my body as I move on each day. The cadiovascular system pumps blood through the heart and systems continuously, through its specific pathway. The blood is helpful in transporting, regulating, and fighting to keep our bodies functioning. Microbes live everywhere around us, and keep a balanced environment, but also causes diseases. Immunity keeps our bodies out of harms way, with the help of WBC and immunizations. AIDS is an unfortunate disease that destroys the T cells in the body, weakining the immune system. Keeping a healthy, productive lifestyle will hopefully keep my body strong and ward off any stray pathogens!
WORKS CITED:
Mader, Sylvia S. Human Biology. Boston: McGrawHill Companies, Inc. 2008.
Quotes
http://en.wikipedia.org/wiki/heart and RBC
pictures of heart, arteries, RBC
www.mhe.com/biosci/es[/2001_saladin/folder_structure/tr/rr3/slo.index.htm
picture of capillary
http://training.seer.cancer.gov/
picture of blood composition(plasma and formed elements)
http://www.biology.arizona.edu/immunology/tutorials/AIDS/impacts.html
pciture infected cell/helper T cell
SELF and UNIT EVALUATION
2. What two aspects of my submitted assignments do I believe could have used improvement? Improvement could probably be found in both the Unit reviews: adding more detail and summarizing those ideas. If I had more time to work on the cell model, I probably could have integrated more information.
3. What do I believe my overall grade should be for this unit? I'm not sure how you grade, or how precise or accurate our labs need to be. For the hours, days, struggle, frustration, and relief of finishing in time I would hope to see an A on this unit. Its a focus factor to help get me through this condensed course, knowing I can do this :)
4. How could I perform better in the next unit? Now that I am aware of all the information that is involved in each unit, and approximately how long it takes me to complete something; time management is my main goal to work on. Setting more time, so I don't feel rushed or aggravated.
Unit ?
1. At what moment during this unit did you feel most engaged with the course? Working hands on with the cell model, and transferring my image into words. This gave me a better understanding of the cell life, DNA, and mitosis.
2. At what moment did you feel most distanced from the course? It took me a few tries to learn the microscope lab. For some reason my sound didn't work, and I found it easier to follow along with the computers narration.
3. What action that anyone(teacher or student) took during this unit that find most affirming and helpful? Having guidelines to follow were a big benefit. It gave me a general idea what to focus on.
4. What action was most puzzling or confusing? This is still frustrating to me: When working on a write-up, and inputting pictures, if I accidentally pressed the backspace one to many times my picture disappeared!!! I haven't found a undo button, therefore, I have to go through and re-arrange my photo!
5. What about this unit surprised you the most? Being able to finish all of the course context in a matter of 2 weeks on top of working, and other classes!! Its amazing what a person can do.
Friday, June 15, 2007
The Endless Tunnel- Ethical Issue Essay
Picture a mouse scurrying along the tall, white walls of a maze. His speedy action gets him to the end of the maze, and is now able to rest. Even though this mouse appears to be like any other mouse, it happens to be a cloned mouse. Mice are commonly used for research. Unfortunately, these little, cloned, creatures live a short unhealthy life. I personally do not agree with all the technology researchers/scientists work and experiment with. While reading these articles, I still firmly disagree with cloning. Life is not made to be sandwiched in a test tube, in hopes to survive a healthy, prolonged life! Three different types of cloning are Recombinant DNA Technology, Reproductive Cloning, and Therapeutic Cloning. The unknown question lingering is, cloning humans the next step?!
Since the 1970's, Recombinant DNA Technology(DNA cloning) has been known as the common practice in molecular biology labs. DNA cloning is when a piece of DNA is transferred to another organism(plasmid, virus, bacteria) that is a self replica of the gene. This study is used to create identical information, to study off of. An example is, DNA cloning of insulin. This process was done by injecting an insulin gene into a vector, E.coli cell, that produces a chemically identical form of insulin. It is said to be reliable for those individuals struggling with high blood glucose levels in Diabetes. This form of insulin is actually used in majority of insulin dependent individuals. There will always be an individual who will have a adverse reaction to this type of insulin, and researchers continue watching for these kinds of risks. There is a dangerous part, which involves a possible contamination during the purification process. I give insulin to a lot of my diabetic dependent patients, but I'm not sure what the insulin is made of. Therefore I'm not sure what my point to make is. The article states many diabetics are currently using this insulin, therefore it has been tested and is effective.
Reproductive Cloning to me is a controversial subject in itself. The well known sheep, Dolly, was cloned in 1997, but it actually took 276 attempts. This type of cloning is mainly focused on animals. To repopulate endangered animals, those that have difficulties breeding, or for research purposes. I don't see this as being useful. There is obviously a reason for endangered animals, possibly because there are plenty in the world. The wild ox, an endangered animal, was cloned but died, 18 hours after birth due to an infection. Is there a reason it died? Was there an error, or was it meant to be? God miraculously gives, but He also takes away. And what is the purpose of trying to re-create another species? This type of cloning is not identical, but has similar DNA structures. Reproductive Cloning has egregious errors to take into account. A few are programming issues, high death rates, deformities, and disabilities. I don't see why you would want to take the chance and watch an animal suffer through these endless possibilities. Animals aren't capable of expressing their feelings, and what if that part of the brain was a deformity? What if they suffered their short life in pain due to a scientific error?
Therapeutic Cloning is an "embryo cloning." Bio-medical researchers find this cloning important to them. It is a process of storing stem cells in order to study development or attempt to treat diseases. The future focuses are to treat: Alzheimer's, Cancer, and Heart disease. It would be a miracle to find a cure for these diseases; since they have always been an issue and are the top leading causes of death. We are born, we live and we die. If we had a cure for everything in this world, life would seem endless. Don't misjudge me, I think it would be a blessing to find a cure for these diseases, but it almost seems impossible. Embryo cloning is a process that destroys the original embryo, after a specific cell is placed. Which raises a question, why would you destroy and original work of art only to create a new piece of art? An amazing percentage while reading this article on cloning is, 90% of cloning attempts FAIL! It also stated that many of the cloned animals do not live long enough to generate data. We all have personal beliefs and ideas pertaining to our lives and that of animals surrounding the world, but is it possible to stop recreating?
In conclusion, for the most part I do not agree with cloning. I mentioned numerous times, but it does not seem ethical to re-create a new life, whether it be a human or an animal. DNA is full of options, but with many unkown consequences. Cloning humans has and always will be a debate to try and sort through. But, the article states that the U.S. Congress is leaning towards banning human cloning. There are too many unknown questions and concerns that linger the idea of a human replica. Would they have mental dysfunctional problems: cognitive, motor,speach? Cloned animals have already proved to have problems, what makes us certain a human would not? Scientists also feel it is an irresponsible, dangerous attempt. Cloning is a topic of discussion, but with the techonology in today's world, is an endless process of possibilities.
CELL MODEL- DNA/CELL GENETICS
Inside of the nucleus are numerous chromosomes, which would be represented as the black pipe cleaners, the yellow ball is the centromere that holds the two chromosomes together: forming sister chromatids(the two small pieces of pipe cleaner). The sisters are identical, in that they have the exact genes. Each chromosome had a DNA double helix. Which is discussed below.
The picture above shows a structure of a DNA double helix, which is two stranded molecule full of nucleotides. Each side of the DNA, nucleotide, is made up of 3 units: phosphate, pentose sugar, and a nitrogen-containing base. Notice in the picture the red and white balls represent the sides of the ladder, which are composed of phosphate and sugar. The hydrogen consists of 4 different bases: Adenine(A), Guanine (G), Thymine(T), and Cytosine (C). Again notice in the picture that the steps to the ladder are composed of the bases just mentioned. Orange(A), Yellow(T), Green(G), and Blue(C). In between each ball is a small piece of black pipe cleaner (which represents the hydrogen bond). If this ladder were twisted the following pairs would occur: A-T, G-C.
During DNA replication: one side of the ladder remains as it is, while the other is away being formed as a new strand. Just remove one side of the ladder, the other side is getting ready to begin a new replica. The final DNA molecule consists of the original and new strand.
During transcription, a strand of mRNA, per the book, forms that is "complimentary to a portion of DNA." If you were to take a picture, as noted above, the two strands are a copy of each other. While clicking the camera, the strand of mRNA sneaks in and develops into a complementary base joined with the DNA bases. Although the DNA is a double strand and mRNA is a single strand. On the other hands, translation refers to the information in a different code. The green beads represent an enlarged ribosome, where tRNA molecules carry amino acids to the site during translation. During this process, polypeptide(black pipe cleaner) synthesis occurs. The messengers bind to the ribosomes, forming an anticodon(3 complementary bases).
The process of Mitosis:
Picture 1 :
Picture 2:
Picture 3:
Picture 1: The beginning phase of Prophase: At this point there is no nucleolus, and the cell is in the process to divide. The yellow balls(centromeres) are starting to move towards opposite sides of the cell. The black pipe cleaners are the chromosomes (sister chromatids) the pink yarn are spindle fibers.
Picture 2: Metaphase: The chromosomes are lined up at the equator of the cell, and the spindle fibers have attached to the centromere.
Picture 3: Anaphase: The centromeres split from the sister chromatids(forming daughter chromosomes), and push away to opposite ends of the spindle. This process enables that each cell will receive the same gene.
Picture 4: Telophase: The chromsomes eventually end up at opposite sides of the cell. The spindles begin to disappear. The nucleolus appears, and there are two cells at opposite ends with DNA.
In conclusion, this model has helped me better understand different parts/functions inside of the cell. Although, with the compendium review having to explain different parts and processes, I feel like I was repetative, or may not have included some parts since I discussed them prior. DNA is a very in depth concept to learn. It may seem easy to say its purpose is to pass on genetic information, but that doesn't seem to justify all the work it actually does. All of the living parts inside of the cell work to together to complete their daily chores. Similar to the daily process of learning.